• Sample collection for a cohort is often carried out

  2018-10-23

  

  Sample collection for a cohort is often carried out at the time of diagnosis, time of treatment or time of screening of healthy individuals, and not confined to a certain time of the year. This implies that environmental factors, such as pollen concentration in the spring, may cause downstream effec

• Machine learning is a branch

  2018-10-23

  

  Machine learning is a branch of AI-based methods that we have applied to examine pathophysiological and clinical parameters as well as therapeutic outcomes in the past, whereby it outperformed standard statistical inference with datasets of as little as 28 patients (Chigutsa et al., 2015; Gumbo et a

• sulfanilamide The extracellular matrix ECM is important for

  2018-10-23

  

  The extracellular matrix (ECM) is important for the integrity of the aortic wall and mutations in ECM genes such as Fibulin-4 and Fibrillin-1 hence lead to aneurysm formation. Genetic studies in Fibulin-4 and Fibrillin-1 mutant mice implicated dysregulation of the TGF-β pathway as an important hallm

• In accordance with the results of other

  2018-10-23

  

  In accordance with the results of other previous clinical studies, in this study the presence of maternal antibody was also suggested in infants monoclonal lenvatinib also correlated with serum neutralization titers. The kinetics of PLNA in samples of children aged at 25 to 36months old and adults

• As opposed to schwannomas other driver mutations

  2018-10-23

  

  As opposed to schwannomas, other driver mutations have been identified in meningioma, but those are mutually exclusive of Merlin (Clark et al., 2013). In order to keep the genetic background consistent with schwannoma, we analysed only Merlin-deficient WHO grade I meningiomas. Comparative functional

• So far RIO kinases have been

  2018-10-23

  

  So far, RIO kinases have been mostly studied in yeast, but the few studies addressing their function in mammalian cells identified an important role of all three family members in ribosomal biogenesis (Baumas et al., 2012; Ferreira-Cerca et al., 2014; Ferreira-Cerca et al., 2012; Turowski et al., 20

• The CS SVM classifier can select a small subset

  2018-10-23

  

  The CS-SVM classifier can select a small subset of stage II and III patients who can specifically benefit from 5-FU/oxaliplatin chemotherapy. Patients identified as high CS-SVM benefited significantly from chemotherapy in the training cohort (DFS, 0.001; OS, 0.0003; Fig. 5). In contrast, low CS-SVM

• Based on these findings we have proposed

  2018-10-23

  

  Based on these findings we have proposed a working model that Dsg3 competes with inactive Src for binding to the scaffolding domain of caveolin-1, and thus causes Src to release from binding to caveolin-1, that leading to its auto-activation (Fig. 5B). This working model opens up a new avenue for fu

• enzyme substrate Based on these findings we have proposed

  2018-10-23

  

  Based on these findings we have proposed a working model that Dsg3 competes with inactive Src for binding to the scaffolding domain of caveolin-1, and thus causes Src to release from binding to caveolin-1, that leading to its auto-activation (Fig. 5B). This working model opens up a new avenue for fu

• Oversized preliminary clusters were selected

  2018-10-23

  

  Oversized preliminary clusters were selected for subsequent splitting by agglomerative hierarchical clustering based on a criterion of (mean number of marked minutiae per examiner) >1.5. This arbitrary threshold was selected because (1) automated splitting of clusters meeting this criterion was high

• br Para cerrar escapar del g nero

  2018-10-22

  

  Para cerrar: ¿escapar del género? Preguntarse si el género es un significante vacío permite considerar la importancia de pensar después el espacio semántico construido por dicho término como el lugar potencial de un desacuerdo —dado que los múltiples significados posibles están en debate constant

• Introduction The global emergence of resistance to antimicro

  2018-10-22

  

  Introduction The global emergence of resistance to antimicrobial agents is increasingly limiting the effectiveness of current drugs, especially in immuno compromised patients. Drug resistance, especially by bacteria and fungi, is one of the major concerns to public health and scientific communitie

• br Conclusions In conclusion EA

  2018-10-22

  

  Conclusions In conclusion, EA irrigation and PUI were more effective than the CHX final rinse and Ca(OH)2 dressing in eliminating bacteria from infected root canals after SAF instrumentation. The presence of remnant bacteria after chemomechanical preparation using SAF and the supplementary effec

• dopamine beta hydroxylase Introduction In the midst of the d

  2018-10-22

  

  Introduction In the midst of the detrimental effects of unstable movement in exchange rate, the negative penalties of exchange rate volatility are of great concern. High uncertainty of exchange rate makes expectations over the future price level more uncertain. In a country where the economy depend

• This study deviates from other studies in a

  2018-10-22

  

  This study deviates from other studies in a number of ways. Firstly, we study institutional quality along with other variables specifically financial factors that determine corporate investment. Our choice of Nigeria is based on the fact that the country is experiencing high rate of deficiencies in

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