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br Cer signaling roles that regulate cellular
2018-11-15
Cer signaling roles that regulate cellular functions The first demonstration of a Cer signaling role (to induce erythroblast maturation) was in 1974. The first barrier Cer studies, reported in 1975 by Gray and Yardley, initiated the field of skin Cer research. In contrast, Cer signaling studies w
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br The structural maturations from desmosomes to corneodesmo
2018-11-15
The structural maturations from desmosomes to corneodesmosomes Desmosomes connect two adjacent keratinocytes with transmembrane desmosomal cadherins, which are mainly Dsg1–4, and Dscs 1–3. Their intracellular C-terminal halves bind to Armadillo proteins: plakoglobin (PG), plakophillins (Pphs), p1
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Histopathological findings vary according to the clinical st
2018-11-15
Histopathological findings vary according to the clinical stage of the disease. In the second stage of the disease, diagnostic findings will include paleness and vacuolization appearing in the upper EHT 1864 cells, eosinophilic intracytoplasmic inclusion bodies in vacuolated cells, and mononuclear c
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The genotype and allele frequencies of the DFEB G A
2018-11-15
The genotype and allele frequencies of the DFEB1 −20G>A (rs11362), −44C>G (rs1800972), and −52G>A (rs1799946) polymorphisms in psoriasis patients and controls are presented in Table 2. Some of the study participants could not be genotyped for the polymorphisms because their DNA samples had been used
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The expressions of major axis
2018-11-15
The expressions of major axis a and minor axis b of ellipse are If the ellipse equation is transformed from the projectile-target frame to the ground frame, then the standard equation of ellipse is obtained as follows Eq. (9) is converted into a general formulawherewhere , . The general formulas o
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Two novel triterpene glycosides saponins have been
2018-11-15
Two novel triterpene glycosides (saponins) have been isolated from M. pigra L. leaves. The aglycone of both compounds was identified as machaerinic Deferoxamine mesylate and substituted at position C-3 by an identical oligosaccharide chain and at position C-21 by either a Z/E-methoxy cinnamic unit
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The rest of the paper will
2018-11-15
The rest of the paper will be organized as follows: Section 2 will be theoretical background and literature review, Section 3 will be conceptual model and hypothesis, Section 4 will be on research methodology, Section 5 will be research results, Section 6 will be discussion of the findings and Secti
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The first group of sculptures
2018-11-14
The first group of sculptures to be displayed in the new Hall consisted of the awesome marbles of the Temple of Apollo Sosianus. Today, three beautiful columns of the Temple, which are placed on their podium and surmounted by the corner of the entablature, have been recomposed and are placed next to
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BRIGHT was previously identified by
2018-11-14
BRIGHT was previously identified by mass spectrometry (MS) as a secondary binding partner of enforced expression of NANOG in mESCs (Wang et al., 2006), but no follow-up analysis was performed. Employing coimmunoprecipitation in mESCs, we confirmed endogenous interactions of BRIGHT with NANOG as well
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Main Text br Acknowledgments I have been fortunate
2018-11-14
Main Text Acknowledgments I have been fortunate to work with tremendous mentors, colleagues, and students throughout my career and I am grateful for their past and current support. Research in my laboratory is supported by the NIH, the New York Stem Cell Foundation as a New York Stem Cell Founda
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In Brazil the Pereskia aculeata Miller plant
2018-11-14
In Brazil, the Pereskia aculeata Miller plant is popularly known as ora-pro-nóbis (OPN). It belongs to the cactaceae family and is used as a nutritional supplement due to its protein, fiber, iron and calcium content. This non-conventional vegetable has succulent leaves, is edible, and can be used in
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In addition to the burden on the population it is
2018-11-14
In addition to the burden on the population, it is hypothesized that the considerable health and care burden of AD will impose a large economic burden throughout affected economies. Previous economic studies estimate the 2009 worldwide cost of dementia to be US$421 billion and attribute 10% of the g
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Phos-tag manufacturer The Scinicariello et al study has seve
2018-11-14
The Scinicariello et al. study () has several limitations and its results should be interpreted with caution. Because phthalates are metabolized and excreted rapidly, a single-spot urine exposure measure may not reflect an individual\'s long-term exposure level and outcomes of interest may be influe
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GSK461364 In pursuit of improving the identification and
2018-11-14
In pursuit of improving the identification and profiling of low-abundance peptides, we developed a streamlined, mass spectrometry-based platform for the characterization of low-abundance GSK461364 in blood and in tissue. As illustrated in Fig. 1, the developed pipeline involves an isolation and fra
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High levels of environmental exposure to peanut due to
2018-11-14
High levels of environmental exposure to peanut due to household consumption during infancy have been related with sensitization (Fox et al., 2009). There is a positive correlation between high peanut consumption and the presence of peanut proteins in the house dust (Brough et al., 2013; Trendelenbu
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