• If two level fractures were

  2018-11-06

  

  If two-level fractures were excluded in both groups, the pregnane x receptor exposure was improved in the IGS group and the mean DAP values of the operator decreased at all measured points. With the fluoroscopy-based IGS system, the yielded values were reduced from 18.87 (SD = 11.50) mGy to 3.34 (S

• br Conclusion Since minimally invasive cardiac surgery

  2018-11-06

  

  Conclusion Since minimally invasive cardiac surgery was introduced, there has been a significant expansion in popularity and experience. Various techniques for obtaining appropriate exposure have been developed and put into practice. Regardless of the variety of surgical approaches, the overall o

• br Conclusion br Introduction br Case report A year

  2018-11-06

  

  Conclusion Introduction Case report A 38-year-old woman was injured in a domestic dispute with her ex-husband. She was stabbed in her belly and splashed with sulfuric acid. Upon presentation to our emergency department, a physical examination showed one 5-cm-long, longitudinal, penetrating

• Clinical data including visual analog scale VAS scores mm

  2018-11-06

  

  Clinical data, including visual analog scale (VAS) scores (0–100 mm), ROM of the joints, and functional scores, were assessed before and 3 months after surgery. The functional scores for each joint were separately evaluated using exclusive scales including the Lysholm knee scale (0–100 points), Mayo

• The following are the supplementary related to this article

  2018-11-06

  

  The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä

• The present study has extended our previous

  2018-11-06

  

  The present study has extended our previous observations (Wang et al., 2009) that ACMs derived from astrocytes stimulated by LPS for different duration exerted distinct roles on NSCs. Previous studies showed that the factors produced by activated astrocytes varied considerably with the nature, inten

• We demonstrated that the PI K AKT signaling

  2018-11-06

  

  We demonstrated that the PI3K/AKT signaling pathway plays important roles in regulating hUCBSC differentiation and maintaining the pluripotency of hESCs (Yu et al., 2012). Furthermore, mTOR/p70S6K, a major downstream effector of PI3K/AKT signaling, was found to be phosphorylated, suggesting that HMG

• Another recent initiative is ISSCR Connect an

  2018-11-06

  

  Another recent initiative is ISSCR Connect, an online educational portal. The goal of ISSCR Connect is two-fold: first, to enhance the experience of those attending the ISSCR meeting, and second, to provide members with additional educational opportunities on a year-round basis and expand their acce

• Inner pillar cells express Fgfr which

  2018-11-06

  

  Inner pillar cells express Fgfr3, which may contribute to their capacity for regeneration (Jacques et al., 2007). Supporting cells in the chicken basilar papilla express Fgfr3, which is transiently downregulated during hair cell regeneration (Bermingham-McDonogh et al., 2001). Fgfr3−/− mice lack inn

• Gene expression is regulated by complex coordinated

  2018-11-06

  

  Gene expression is regulated by complex coordinated processes, including chromatin remodeling, post-translational modifications of histones, and incorporation of non-allelic histone variants. The histone variant H2AZ constitutes only a few percents of the total H2A cellular pool (). However, H2AZ is

• In this study we report the creation of the first

  2018-11-06

  

  In this study, we report the creation of the first genetically modified large animal model of a metabolic liver disorder, HT1, in pigs that are deficient in FAH, an enzyme that catalyzes the last step in tyrosine metabolism (Lindblad et al., 1977). Based on the results presented here, we believe FAH

• The identification of new stem cell markers characteristic o

  2018-11-06

  

  The identification of new stem cell markers characteristic of a phenotypic subset or experimental state remains a major ap1 research goal. Researchers may wish to assess the uniqueness of an expression profile before embarking on experiments that rely on a reporter gene or antibody to select for a

• Defining regeneration as the replacement of

  2018-11-06

  

  Defining regeneration as “the replacement of missing structures following injury” (Morgan, 1901), compensatory lung growth after pneumonectomy is an extraordinary example of mammalian tissue regeneration. After left pneumonectomy, the missing lung tissue is not regrown orthotopically in the left hil

• Placental growth factor PlGF is an angiogenic

  2018-11-06

  

  Placental growth factor (PlGF) is an angiogenic protein often highly upregulated in solid tumors contributing to their growth and survival (Kim et al., 2012). PlGF can promote angiogenesis either by directly stimulating endothelial cell growth or by recruiting pro-angiogenic cell types. Of the two m

• Ramelteon It is well established that a host of factors with

  2018-11-06

  

  It is well established that a host of factors within the injured microenvironment are capable of activating circulating Ramelteon and platelets and thus permitting their endothelial adhesion during inflammatory processes (Mori et al., 2005a; Vowinkel et al., 2007; Sprague and Khalil, 2009; Santen e

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