• Pilsicainide might increase hERG proteins via facilitating t

  2019-06-11

  

  Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica

• Eligio Mar a Ancona Castillo naci en la ciudad

  2019-06-11

  

  Eligio María Ancona Castillo nació en la ciudad de Mérida, el 1° de diciembre de 1836. Después de cursar los estudios elementales en la escuela de su padre, inició los cursos preparatorios en el Seminario Conciliar de San Ildefonso. Más tarde se inscribió en la Universidad del Estado para iniciar la

• As la historia a la vez

  2019-06-11

  

  Así, la historia, a la vez ejemplar e ilustrativa, es un elemento aglutinador de la identidad del pueblo mexicano pues conforma la narración unificadora necesaria para fusionar, en una identidad única, a la sociedad mexicana. Por ello, para Vigil, la enseñanza de la historia convertiría “a los habit

• In the current study we

  2019-06-11

  

  In the current study, we first isolated primary HSCs from rat liver and then treated the ask1 inhibitor with alcohol. As shown in Fig. 1, the mRNA levels of PCBP2 and type I collagen were increased significantly. In addition, the type I collagen mRNA level was more significantly increased in primar

• In several Western reports from large scale comparative

  2019-06-11

  

  In several Western reports from large-scale comparative studies and epidemiological surveys, there was no significant difference in the incidence of thromboembolism between paroxysmal and persistent AF patients [46,47]. Data from our institution suggested that the incidence of cardiogenic thromboemb

• Introduction By catalyzing post translational acetylation of

  2019-06-10

  

  Introduction By catalyzing post-translational acetylation of lysine residues, the histone acetyl transferases (HAT) CREBBP and EP300 moderate the activities of both histone and non-histone proteins. This regulates vital cellular processes such as cell cycling and apoptosis by modulating chromatin s

• An ERP in the ECG has been shown to

  2019-06-10

  

  An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A

• En ese contexto Mart nez Estrada que se encontraba en

  2019-06-10

  

  En ese contexto, Martínez Estrada, que se encontraba en México, fue encargado de recordar p53 tumor suppressor don Alfonso Reyes en representación de Argentina, y de pronunciar las palabras en reconocimiento a los 19 años de Cuadernos, junto con el poeta español Francisco Giner y el filósofo mexican

• hif pathway As long as developing world health systems

  2019-06-10

  

  As long as developing-world health systems are ill prepared to offer safe anaesthesia and intensive care to patients in need of surgery, surgically treatable conditions will remain leading causes of death, the world will lose trillions of dollars in gross domestic product, and we in the global healt

• Funding US Centers for Disease Control and Prevention US Pre

  2019-06-10

  

  Funding US Centers for Disease Control and Prevention, US President\'s Malaria Initiative, Doris Duke Charitable Foundation, and Alpha Omega Alpha Honor Society. Declaration of interests Abstract Background Injuries are the cause of almost 6 million deaths every year, with 15–20% of these assoc

• In addition to the effect

  2019-06-10

  

  In addition to the effect of vector control against malaria and HAT on lymphatic filariasis endemicity over several years, recent improvements in NTD mapping strategies and diagnosis of have greatly affected the outcomes of surveys undertaken to establish the burden of NTDs in Africa. More accurate

• br In the past year migration to

  2019-06-10

  

  In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm

• br Materials and methods br Results Shortening of the QRS

  2019-06-10

  

  Materials and methods Results Shortening of the QRS duration in 7 and lengthening of the QRS duration in 3 of the 24 patients were observed during RV pacing at a mean pacing ion channels length of 346±37ms and 258.3±14.4ms (Fig. 1; Tables 1 and 2). The mean shortening of the QRS duration was −

• br Clinical characteristics Brugada syndrome is more

  2019-06-10

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

• Although no GWAS results have been reported so

  2019-06-10

  

  Although no GWAS results have been reported so far from Asian populations, the candidate gene approach identified SNPs in 4q25 and 1q21 as being associated with AF in Asian populations [19,20]. Conflicting data are reported in terms of 16q22; it is associated with AF in Chinese Han [37], but not in

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