• Pain flare defined as a temporary worsening

  2019-05-30

  

  Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte

• To date over mutations in KCNQ

  2019-05-30

  

  To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [

• In a recent study Nademanee et al reported additional eviden

  2019-05-30

  

  In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation

• De acuerdo con el historiador argentino la

  2019-05-30

  

  De acuerdo con el historiador argentino, la independencia de las colonias españolas en América es el resultado de una degradación del poder español que había comenzado desde 1795. En primera instancia, el poder de la Corona española se hacía cada vez más lejano, pues la pérdida de la guerra de Españ

• The combination therapy was exceedingly well tolerated witho

  2019-05-29

  

  The combination therapy was exceedingly well tolerated without any side effects to either drug. Remarkably, despite an advanced PV-stage the JAK2V617F allele burden was rapidly lowered from 90% mutated put you down at referral to 59% at 6 months, 28% at 10 months and 12% at 16 months of therapy (Fig

• Phos-tag Acrylamide We have received funding from the

  2019-05-29

  

  We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid

• pkm2 br Methods This prospective study was conducted at the

  2019-05-29

  

  Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor

• Conflicts of interest br Introduction

  2019-05-29

  

  Conflicts of interest Introduction Hepatocellular carcinoma (HCC) is one of the most common cancers and is the second leading cause of cancer death worldwide. In 2012, 782,500 new HCC cases and 745,500 deaths were caused by this persistent disease worldwide, with about 50% of the total number of

• br Intrauterine insemination IUI is one of the more

  2019-05-29

  

  Intrauterine insemination (IUI) is one of the more widely used fertility treatments, and often suggested as the first choice for infertile couples with cervical infertility, mild male factor infertility, anovulation, mild or minimal endometriosis, and unexplained infertility with at least one pate

• In the American College of Chest

  2019-05-29

  

  In 2013, the American College of Chest Physicians provided a guideline to the preoperative physiological assessment of patients being considered for surgical resection of lung cancer. It has been recommended that patients must be assessed by a multidisciplinary team before operation, regardless of a

• Although preoperative rehabilitation may have a strong

  2019-05-29

  

  Although preoperative rehabilitation may have a strong impact on survival if additional patients are qualified for curative resection, yet strong evidence remains lacking to support the regimens for patients who have lung cancer. This may be due to, in part, the relatively brief meclofenamate of tim

• br In Sanguinetti et al

  2019-05-29

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

• br Material and methods br Results A

  2019-05-28

  

  Material and methods Results A total of 4014 subjects were enrolled and registered during the initial recruitment CX-5461 from September 2013 through March 2015. In total, 167 subjects were excluded because of missing pivotal data such as height, body weight, or age (date of birth). Finally,

• To assess quality independent from quantity Imamura

  2019-05-28

  

  To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i

• Tambi n debemos tener presente el

  2019-05-28

  

  También debemos tener presente el horizonte en el que se inscriben colecciones como la aquí revisada. Si aceptamos que nos encontramos bajo un panorama de fragmentación del conocimiento y segmentación de las disciplinas, se muestra fundamental la recuperación de la toma de partida por la cultura, en

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