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br Dissemination permissive characteristics of the
2019-07-01
Dissemination-permissive characteristics of the BM vascular niche Sinusoids (type L capillaries) are the most abundant blood vessels in bone and widely distributed throughout the bone marrow cavity [8]. Sinusoids in bone are discontinuous single layer of endothelial LY83583 devoid of pericytes.
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br Quentin Eichbaum and colleagues describe how new medical
2019-07-01
Quentin Eichbaum and colleagues describe how new medical schools in Africa have developed curricula that include community and rural health components, long-term family attachments, and admission processes that are more equitable for disadvantaged students. All these worthwhile innovations have be
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Pero m s all del folclore
2019-07-01
Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber
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br La subjetivaci n pol tica de la Coordinadora es
2019-07-01
La subjetivación política de la Coordinadora es quizá una de las más sofisticadas interpretaciones dentro del movimiento mapuche (sin contar MK0752 molecular su sector intelectual), sobre su propia condición de dominados. Nos ha interesado narrar en la primera sección de este texto las condiciones
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br Al hablar del requisito sine qua
2019-07-01
Al hablar del requisito sine qua non de conocer la lengua uitoto, vale la pena hacer un paréntesis para repasar el estado de los estudios propiamente lingüísticos. Diferentes recuentos bibliográficos sobre las fuentes para el estudio de las lenguas de la Amazonia colombo-peruana, reportan que los
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Eosinophilia often occurs as a secondary process due to
2019-07-01
Eosinophilia often occurs as a secondary process due to parasitic infections, allergy, SGI-1776 disease, malignancy, or drug reactions. When secondary causes of eosinophilia are excluded, one must consider HES, which is defined as a peripheral eosinophil count of greater than 1.5×109/L on at least 2
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Introduction Acute erythroleukemia AEL is a rare subtype
2019-07-01
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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br It is encouraging to read in the Article by
2019-06-29
It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara
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Nowadays other Brazilian HIV patients were enrolled in the
2019-06-29
Nowadays other 20 Brazilian HIV+ patients were enrolled in the second-phase of Lu et al. clinical trial [3], and biologic samples are becoming available for novel investigation. All this considered and taken into account that the intrinsic ability of each HIV+ individual to counteract HIV-1 result
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Another mechanism is that J waves represent
2019-06-29
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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Introduction The assessment of hormonal receptor HR and huma
2019-06-29
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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BML-277 br Conflict of interest br Authors contributions br
2019-06-29
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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br Interpretation of identified genetic variants
2019-06-29
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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Eastern European countries have undergone
2019-06-29
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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There are important methodological issues affecting the stud
2019-06-29
There are important methodological issues affecting the study of child mortality inequalities on the basis of survey data. McKinnon and colleagues relied on rigorous analytical tools to study these changes, and in some aspects—for example the graphical display of the statistical significance of chan
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