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In the days before Christmas adverse
2019-05-08
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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br It is encouraging to
2019-05-08
It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara
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br Methods br Results br Discussion ICC
2019-05-08
Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi
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Paisey et al recently proposed a simple technique for
2019-05-08
Paisey et al. recently proposed a simple technique for recognizing an MI block. In their study, an abrupt change of the CS activation pattern during RF application, under left atrial appendage pacing from a distal-to-proximal to proximal-to-distal direction provided a reliable assessment of MI condu
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br Commentary Recordings of the activation sequence
2019-05-08
Commentary Recordings of the activation sequence from the CS during tachycardia are expected to help discriminate among atrial tachyarrhythmias [2]. During ongoing typical CCW AFL, most of the CS is activated from proximal to distal, because the CS musculature, by being continuous with the RA myo
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br Conclusions The experimental results in isolated sheep he
2019-05-08
Conclusions The experimental results in isolated sheep hearts presented herein clearly demonstrate that self-sustained rotors exist in the atria. Such rotors are the high frequency sources that give rise to the complex patterns of activation that characterize AF. More specifically, our results su
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Recently emerging data suggest that lower frequency of IV
2019-05-08
Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f
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Pharmacokinetics analysis of AT on SCID
2019-05-08
Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu
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Patient a year old man with RAEB and severe
2019-05-07
Patient 2, a 54-year-old man with RAEB 2, and severe chronic obstructive pulmonary disease, struggled through induction chemotherapy with daunorubicin plus cytarabine (DA) 3+10. Second DA 3+8 produced delayed hematopoietic recovery. CR1 was documented after course 1 and lasted 18 months. Relapse was
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NCS is a rare syndrome In
2019-05-07
NCS is a rare syndrome. In case series of NCS 14–47% were associated with of lymphoproliferative disorders [reviewed in [12]]. Survival is usually dictated by the underlying disease and short in the setting of aggressive malignancies. Since NCS may be a manifestation of an underlying malignancy it h
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amphetamine sulfate br Al hablar del requisito sine qua non
2019-05-07
Al hablar del requisito sine qua non de conocer la lengua uitoto, vale la pena hacer un paréntesis para repasar el estado de los estudios propiamente lingüísticos. Diferentes recuentos bibliográficos sobre las fuentes para el estudio de las lenguas de la Amazonia colombo-peruana, reportan que los
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br Historical overview Before the
2019-05-07
Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the 1-Deoxynojirimycin Supplier muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgemen
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transcription factors br Analysis of mismatch repair functio
2019-05-07
Analysis of mismatch repair function and results Analysis of microsatellite instability: Multiplex PCR amplification of 5 mononucleotide microsatellite loci was performed using the MSI Analysis System (Promega). Amplification products were analyzed using the ABI 3500Dx capillary electrophoresis i
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Dexamethasone with its anti inflammatory properties
2019-05-07
Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro
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ECG changes emerged when creating
2019-05-07
ECG changes emerged when creating a substrate map of the LV (Fig. 2A), near the inferior mitral valve. A long transseptal sheath was introduced into the LV under intracardiac echocardiography guidance without causing an air-embolism. While performing the LV substrate mapping, the long transseptal sh
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