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Eosinophilia often occurs as a secondary process due to
2019-07-01
Eosinophilia often occurs as a secondary process due to parasitic infections, allergy, SGI-1776 disease, malignancy, or drug reactions. When secondary causes of eosinophilia are excluded, one must consider HES, which is defined as a peripheral eosinophil count of greater than 1.5×109/L on at least 2
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Introduction Acute erythroleukemia AEL is a rare subtype
2019-07-01
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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br It is encouraging to read in the Article by
2019-06-29
It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara
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Nowadays other Brazilian HIV patients were enrolled in the
2019-06-29
Nowadays other 20 Brazilian HIV+ patients were enrolled in the second-phase of Lu et al. clinical trial [3], and biologic samples are becoming available for novel investigation. All this considered and taken into account that the intrinsic ability of each HIV+ individual to counteract HIV-1 result
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Another mechanism is that J waves represent
2019-06-29
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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Introduction The assessment of hormonal receptor HR and huma
2019-06-29
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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BML-277 br Conflict of interest br Authors contributions br
2019-06-29
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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br Interpretation of identified genetic variants
2019-06-29
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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Eastern European countries have undergone
2019-06-29
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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There are important methodological issues affecting the stud
2019-06-29
There are important methodological issues affecting the study of child mortality inequalities on the basis of survey data. McKinnon and colleagues relied on rigorous analytical tools to study these changes, and in some aspects—for example the graphical display of the statistical significance of chan
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There was no significant correlation between
2019-06-29
There was no significant correlation between the tHcy level and RBC folate level; therefore, we used two-way ANOVA to analyze the relative contributions of serum folate, the C677T genotype, and vitamin B12 to variations in tHcy concentrations. Intervention studies in humans taking folate and/or vita
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br Sustained monomorphic ventricular tachycardia br Monomorp
2019-06-29
Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr
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However during pacing at the most proximal CS electrodes CS
2019-06-29
However, during pacing at the most proximal CS electrodes (CS 9–10), although the conduction time to the CS 1–2 was prolonged, the septal to lateral activation sequence (CS 5–6 to CS 3–4 to CS 1–2) indicated the presence of residual conduction on the MI line (Fig. 3B). Detailed mapping on the MI lin
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The exact location of the
2019-06-28
The exact location of the APs within the cusps is difficult to determine. The majority of studies used coronary angiography, and less commonly electroanatomical mapping. The morphology of local atrial and ventricular electrograms may be additionally used [1,2]. Mapping within the RCC typically shows
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Si se rescata de estas afirmaciones en primer
2019-06-28
Si se rescata de estas afirmaciones, en primer término, la pretensión crítica realista como fundamento de su propuesta literaria, algunos de los cambios en su entorno cultural cobran relevancia para contextualizar su interés por la ironización de la realidad dentro de la heterogeneidad de su obra. C
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